Skinless: A brilliant medical researcher in his prime is stricken with cancer. Dr. Pete Peele formulates a potential yet unconventional cure for his illness but the clock is running out. He fears that he'll die before clinical trials prove the efficacy of the treatment so he decides to make himself a human guinea pig. He feels he has nothing to lose. Unfortunately the cure he hoped for yields unspeakable results. His terrifying transformation drives him to madness and wreaks bloody havoc on those closest to him.